February 13, 2008

E-Bol Super Anabolic Formula by Thermolife 180ct

E-Bol Super Anabolic Formula by Thermolife 180ct

ThermoLife International’s E-BOL is a natural and non-hormonal dietary supplement designed to boost anabolism, recovery, and endurance (among many other things). It has a huge number of other health benefits aside from these, and nearly every positive effect is shown across multiple ingredients. The precision blend of 7 carefully selected ingredients has been painstakingly researched to provide maximum health benefits completely naturally, with no side effects. Below are detailed descriptions of each of the 7 ingredients in E-BOL with outlines of what they do, and with each claim made backed up by scientific research. Ecdysterone (from Rhaponticum Carthamoides): Ecdysterone is a hormone present in plants and insects and has a typical steroidal chemical structure. Its effects in humans are drastically different than they are in plants meaning that it is non-hormonal in humans and has none of the typical side effects associated anabolic steroids (a completely different class of hormone molecules). It has been touted as `the Russian Anabolic Secret’ and has been shown in many studies to increase anabolism and muscle growth as well as endurance (drastically). One key thing to keep in mind when looking at an ecdysterone based supplement is the plant source from which it was extracted. ThermoLife uses ultra high purity extracts specifically sourced from the Rhaponticum carthamoides plant and standardized for 99% ecdysterone, the purest ecdysterone extract in the entire in the world. When looking at any product containing ecdysterone it is important to know that any and all studies showing anabolic activity from ecdysterone used extracts from Rhaponticum Carthamoides plants, the same material used by ThermoLife. These studies observed steroidal like increases in anabolism and erythropoiesis (red blood cell differentiation) similar to the popular drug nerobol (D-BOL) but without the androgenic effects (1,2,3). Many other studies have been done on ecdysterone and Rhaponticum carthamoides, and effects such as (4) increased endurance (perhaps due to their ability to increase red blood cell production), (5) strong antioxidant activities, (6) hypolipidemic effects (cholesterol lowering), and (7) anti-microbial effects have been widely observed. Ecdysterone supplementation in quails (8), mice (9) and pigs (10) has shown remarkable increases in muscle growth, protein synthesis, and greatly increased quality of animal products. These effects have been seen on numerous different animals in many different medical studies, as well as in humans. A study done on humans showed significant increases in anabolism, as well as fat loss (11). Although the action of these molecules is hormonal in plants (through different biological pathways than in humans), it is not directly so in humans and therefore is considered completely natural and non-hormonal. A proposed mechanism for the anabolic actions of ecdysterone in the body is by means of (12) increasing protein synthesis. It is suggested that this is due to (12) increased ribosome activity and increased speed of assembly of ribosomal subunits into translation complexes (i.e. 80s initiation complex) which synthesize proteins using mRNA (messenger RNA are instructions for protein assembly) as a template. It is also suggested that through this increased ribosomal activity, the speed at which polyribosome units translocate amino acids onto growing polypeptide chains is increased; these combined effects yield overall increased rates of protein synthesis. Another study which demonstrated these effects showed that supplementation with ecdysterone can cause increases in protein synthesis in the liver by as much as 50% (13). Unlike anabolic steroids, which are typically required to promote the sort of anabolic improvements and effects that been previously discussed, ecdysterone does not have any negative impacts on the body’s functions. The effects are quite opposite to the negative sides of anabolic steroids, and studies have shown it to protect liver function (14,15), and scavenge free radicals (5). It has also been suggested that on top of being infinitely safer than the anabolic steroid nerobol (and all anabolic steroids for that matter), it may actually have (4) a wider range of actions and may cause greater increases in endurance in a shorter period of time. The range of positive effects from this compound seem to be endless, and it even has the effects of increasing sexual performance in human males (17), increasing learning and memory in rats (18), and lowering blood pressure (anti-hypertensive) (19). Radix Cyathulae (20% Cyasterone): Radix Cyathulae is a traditional Chinese plant that has been used for centuries to aid in blood stagnation, improve liver and kidney functions, alleviate depressive moods, and help with joint pains. Along with containing the exciting compound ecdysterone (as discussed above), it contains 10 other potent plant sterols with very strong promise for anabolic activity. Among these 10 new ecdysteroids, the most exciting addition is cyasterone. It is a molecule which has similar structural properties to ecdysterone and exhibits many (perhaps more) of the same benefits. The key difference here is that Cyasterone has (20) anabolic effects even greater than those of ecdysterone, and is comparable in this sense to another less known but very potent plant sterol, turkesterone. In order the maximize the anabolic effects of cyasterone, the Radix Cyathulae extract used by ThermoLife International in E-BOL is standardized to at least 80% ecdysteroids. This yields 20% of the total extract being cyasterone and the other 60% being made up of the following 10 additional plant sterols: Isocyasterone 5-Epicyasterone Sengosterone Amarasterone A Amarasterone B Capitasterone Post-sterone Ecdysterone Crustecdysone Precyasterone The anabolic effects of ecdysterone are well studied and it has been shown to be potent enough to be used as its own highly anabolic supplement (i.e. ThermoLife Ecdysten and the Russian drug Ecdysten). The other components listed above on their own have great potential for anabolic activity; however this has yet to be fully studied. Anecdotal evidence suggests that the inclusion of these additional plant sterols provides massively increased synergy and yields unprecedented anabolic activity. The synergy that occurs in the full plant extract as opposed to a single isolated sterol is very powerful and greatly improves all of the positive effects of these compounds (all benefits listed about ecdysterone). These new plant sterols combined with the already well known activities of ecdysterone and the even greater anabolic properties of cyasterone packs a very powerful anabolic punch. The strong effects of these ecdysteroids are not just for muscle growth, and they have been shown to yield impressive increases in endurance, as well as memory and learning (21). These findings indicate that supplementation of plant sterols are not just for bodybuilders (although ideal) and are beneficial for all athletes regardless of their specific sport. The effects seen from Radix Cyathulae are very similar to those listed for ecdysterone (see the section on Ecdysterone for details of effects), such as increased anabolism and muscle growth (16), as well as liver protective effects (3) and neuro-protective effects (22). The antioxidant properties of ThermoLife International’s exclusive Radix Cyathulae extract are very powerful because it has the ability to (23) increase the activity of the enzymes superoxide dismutase and catalase. The reason why this is so profound is because typical free radical scavengers must intercept and neutralize free radicals, which is a second order reaction requiring the chance collision of two molecules. This reaction relies on the probability of two incredibly small molecules spontaneously colliding (not fantastic odds, and is somewhat concentration dependa

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